The Papa test is completely painless, and it is performed by a gynecologist while the woman is lying on a gynecological table. By introducing the speculum into the vagina, the gynecologist displays the neck of the uterus and by using a wooden spatula and a wooden stick wrapped with a wool takes a sample from the back of the vagina, from the cervix part of the neck of uterus and from the cervix. The sample from wooden spatula and sticks is transferred to a small glass that is being immersed in alcohol for the purpose of fixing the cells and is painted with a special method in order to analyze microscopically taken cells.
In clinical practice, the PAPA test was introduced in the fifties of the last century by the American doctor of Greek origin Papanicolau, after which the test was named. Like all the other tests, it is not absolutely unmistakable, and in some cases it can be “false negative” or “false positive”.
In order to avoid false positive and negative results, it is necessary to follow the already mentioned instructions of behavior before the PAPA test, and the taking of the PAPA test and its interpretation should be carried out by experienced and highly qualified doctors of gynecology and cytology.